De-differentiation in thyroid cancer- an increasingly appreciated concept

MircoRNAs in thyroid cancer

Thyroid cancer, which is known as the most common type of endocrine cancer, has seen a growing prevalence in the last few years. On the other hand, only a small percentage of them are associated with malignancy and most of them are benign tumors. Therefore, the first step in the proper management of this type of cancer is to distinguish malignant tumors from benign ones, and today, we are tryin...

Tuberculosis - an under-appreciated disease.

Tuberculosis Worldwide Tuberculosis (TB, as usually abbreviated) is a major cause of morbidity and mortality in many countries, and a signifi cant public health problem worldwide. The World Health Organization (WHO) estimates that there are about 8.8 million new cases of TB and 1.6 million deaths from TB every year.1 Non-compliance with anti-TB drug treatment, or inappropriate treatment, or bot...

De novo thyroid cancer after liver transplantation

Introduction: The occurrence of de novo thyroid cancer following liver transplantation was rare. We reported our case to explore the clinical features, risk factors and preventive measures against the incidence of de novo thyroid carcinoma after hepatic transplantation. Case report: This was a single case report. One female patient, aged 55 years old, undergoing allogeneic piggyback liver trans...

The role of Ile3434Thr XRCC7 gene polymorphism in Differentiated Thyroid Cancer risk in an Iranian population

Background: The aim of this study was to understand any association between differentiated thyroid carcinoma (DTC) and Ile3434Thr XRCC7 gene polymorphism (GenBank accession number: rs7830743). DTC is the most prevalent thyroid neoplasm, which includes papillary and follicular cell carcinoma. XRCC7 gene encodes a protein that functions in non-homologous end joining DNA repair pathway. Non-synony...

An increasingly complex code.